Genome-wide identification of regulatory sequences undergoing accelerated evolution in the human genome
We used DNase I hypersensitive sites (DHSs) to annotate putative regulatory sequences in the human genome and conducted a systematic analysis of accelerated evolution at DHSs in the human genome. Our results strongly suggest that accelerated evolution on regulatory sequences plays important role in the evolution of human specific phenotypes.
Supplementary tables are listed below. See also the whole article in the web site of Molecular Biology and Evolution.