People

Professor:

weidong Tian

E-mail: weidong.tian@fudan.edu.cn

B. E. degree in Biochemical Engineering from Shanghai Jiaotong University in 1995; M. S. degree in Biochemistry from Tsinghua University in 1995 and Ph. D. in Biology from Washington University in St. Louis in 2004. Post-doctoral fellow at Harvard Medical School from 2005 to 2008; Professor of the Institute of Biostatistics, School of Life Sciences, Fudan University, since 2008.

Using statistics, computer science, bioinformatics and other approaches to develop accurate algorithms on predicting gene functions, gene-gene relationships, gene phenotypes, and disease candidate genes; Constructing gene networks to identify gene modules and study the dynamic behaviors of gene modules in disease related gene networks.

Selected Publications;* corresponding author

  • Chen J, Ma M, Shen N, Xi J, Tian W*: Integration of cancer gene co-expression network and metabolic network to uncover potential cancer drug targets. J Proteome Res 2013 DOI: 10.1021/pr400162t.
  • Sun S, Dong X, Fu Y, Tian W* : An iterative network partition algorithm for accurate identification of dense network modules. Nucleic Acids Res 2012, 40(3):e18.
  • Fang Z, Tian W*, Ji H: A network-based gene-weighting approach for pathway analysis. Cell Res (2012) 22:565–580
  • Tian, W., L. V. Zhang, M. Tasan, F. Gibbson, O. King, Z. Wunderlich, J. Park, M. Cherry and F. P. Roth. (2008) “Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function”. Genome biology. 9 Suppl 1:S7.
  • Tian, W. and J. Skolnick (2003). "How well is enzyme function conserved as a function of pairwise sequence identity?" J Mol Biol 333(4): 863-82 (Faculty of 1000 Biology).

Members:

Lab. members

  • PhD students: Li Zixiu, Wang Xiao, Zhang Feng, Chen Xiaoqing, Yan Zijun
  • MS students: Yin Tianshu, Dou Yaguang, Sun Hui, Li Boyi, Wu Yu, Du Hanxiao

Graduated members

  • PhD: Dong Xinran, Lu Yulan, Zhang Jifeng, Chen Jingqi
  • MS: Gong Qingtian, Wang Xinge, Ni Qi, Ning Wei, Hou Ji